Publications
2023
Tissue Biology: In Search of a New Paradigm
Miri Adler*, Arun R. Chavan*, and Ruslan Medzhitov, Annual Review of Cell and Developmental Biology (2023)
Emergence of division of labor in tissues through cell interactions and spatial cues
Miri Adler*, Noa Moriel*, Aleksandrina Goeva*, Inbal Avraham-Davidi, Simon Mages, Taylor S. Adams, Naftali Kaminski, Evan Z. Macosko, Aviv Regev, Ruslan Medzhitov and Mor Nitzan, Cell Reports (2023)
Circuit to target approach defines an autocrine myofibroblast loop that drives cardiac fibrosis
Shoval Miyara*, Miri Adler*, Elad Bassat, Yalin Divinsky, Kfir Baruch Umansky, Jacob Elkahal, Alexander Genzelinakh, David Kain, Daria Lendengolts, Tali Shalit, Michael Gershovits, Avraham Shakked, Lingling Zhang, Jingkui Wang, Danielle Miriam Kimchi, Andrea Baehr, Rachel Sarig, Christian Kupatt, Elly Margaret Tanaka, Ruslan Medzhitov, Avi Mayo, Uri Alon, Eldad Tzahor, bioRxiv (2023)
Shuang Wang, Kenneth Li, Eliana Pickholz, Ross Dobie, Kylie P Matchett, Neil C Henderson, Chris Carrico, Ian Driver, Martin Borch Jensen, Li Chen, Mathieu Petitjean, Dipankar Bhattacharya, Maria I Fiel, Xiao Liu, Tatiana Kisseleva, Uri Alon, Miri Adler, Ruslan Medzhitov, Scott L Friedman, Science Translational Medicine (2023)
2022
Emergence of dynamic properties in network hypermotifs
Miri Adler and Ruslan Medzhitov, PNAS (2022)
Microenvironmental sensing by fibroblasts controls macrophage population size
Xu Zhou, Ruth A. Franklin, Miri Adler, Trevor S. Carter, Emily Condiff, Taylor S. Adams, Scott D. Pope, Naomi H. Philip, Matthew L. Meizlish, Naftali Kaminski, and Ruslan Medzhitov, PNAS (2022)
2021
Senescent cells and the incidence of age-related diseases
Itay Katzir, Miri Adler, Omer Karin, Netta Mendelsohn-Cohen, Avi Mayo, Uri Alon, Aging Cell (2021)
Distinct extracellular–matrix remodeling events precede symptoms of inflammation
2020
Principles of Cell Circuits for Tissue Repair and Fibrosis
iScience (2020)
2019
Continuum of Gene-Expression Profiles Provides Spatial Division of Labor within a Differentiated Cell Type
Miri Adler, Yael Korem Kohanim, Avichai Tendler, Avi Mayo, and Uri Alon, Cell Systems (2019)
2018
Fold-change detection in biological systems
Miri Adler and Uri Alon, Current Opinion in Systems Biology (2018)
Circuit Design Features of a Stable Two-Cell System
Xu Zhou*, Ruth A. Franklin*, Miri Adler*, Jeremy B. Jacox, Will Bailis, Justin A. Shyer, Richard A. Flavell, Avi Mayo, Uri Alon, and Ruslan Medzhitov, Cell (2018)
Endocytosis as a stabilizing mechanism for tissue homeostasis
Miri Adler, Avi Mayo, Xu Zhou, Ruth A. Franklin, Jeremy B. Jacox, Ruslan Medzhitov, and Uri Alon, PNAS (2018)
2017
Optimal Regulatory Circuit Topologies for Fold-Change Detection
Miri Adler*, Pablo Szekely, Avi Mayo, and Uri Alon, Cell Systems (2017)
2014
Logarithmic and Power Law Input-Output Relations in Sensory Systems with Fold-Change Detection
Miri Adler, Avi Mayo, and Uri Alon, PLOS Computational Biology (2014)
